ABSTRACT
Researches on the biomarkers of tumors are very important for their early diagnosis and treatment. Although PSA has been used for over 20 years for screening prostate cancer and evaluating its treatment, the results are not entirely satisfactory. With the deepening of the researches on prostate cancer, a variety of prostate cancer biomarkers have been found. This article presents an overview on the recent advances in the screening for prostate cancer biomarkers.
Subject(s)
Humans , Male , Biomarkers, Tumor , Early Detection of Cancer , Prostatic Neoplasms , DiagnosisABSTRACT
<p><b>OBJECTIVES</b>To present experience on the diagnosis and treatment of urethral condyloma acuminatum (CA) in male patients.</p><p><b>METHODS</b>Twenty-one cases of urethral CA were studied. The lesion of urethral meatus and intraurethal were resected by electrofulguration or operation and Urethroscopy, respectively. All patients were received intraurethral instillation and local therapy of 5% 5-fluorouracil solution.</p><p><b>RESULTS</b>The patients had been followed up for three to twelve months. Cure rate was 76.2%, recurrence rate was 23.89%.</p><p><b>CONCLUSIONS</b>Transurethral endoscopy is a reliable diagnosis and treatment method. Intraurethral instillation and local therapy of 5% 5-fluorouracil solution may prevent the recurrence of CA.</p>